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KMID : 0942820030020020090
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Journal of Korean Brain Tumor Society
2003 Volume.2 No. 2 p.90 ~ p.93
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Supratentorial Papillary Ependymoma Mimicking Astrocytoma and Meningioma
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Lee Seung-Joon
Kim Jeong-Eun
Hwang Sung-Kyun
Jung Hee-Won
Choi Yoon-La
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Abstract
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The authors report a case of papillary ependymoma, which is known to be rare and difficult to diagnose. A 35-year-old
female, who had been previously diagnosed as having anaplastic astrocytoma at the other hospital, was admitted with
headache, vomiting and decreased visual acuity. She had a multicystic tumor in the left parietal lobe on magnetic resonance image(MRI), and initial pathologic diagnosis after surgical resection was papillary meningioma. However, the electronmicroscopy( EM) examination showed findings of papillary ependymoma. In spite of adjuvant radiotherapy, postoperative 1-year follow-up MRI showed recurrence of tumor. The tissue obtained from the recurred tumor showed anaplastic features of dedifferentiated tumor cells with a proliferation index(Ki-67 index) of 10%.
Supratentorial papillary ependymoma is difficult to be diagnosed only by typical light microscopy or immunohistochemistry.
Therefore, ultrastructural study is necessary for diagnosis of papillary ependymoma.
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KEYWORD
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Papillary ependymoma, Electronmicroscopy, Papillary meningioma, Immunohistochemistry
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